Description
D115 – Advanced Pathophysiology for the Advanced Practice Nurse (Objective Assessment)





Question 1
An advanced practice registered nurse (APRN) reviews genetic testing results indicating that a patient has a 45,X karyotype. Which clinical findings should the APRN expect?
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Female sex, short stature, webbed neck, streak gonads, and infertility ✅
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Low birth weight, severe intellectual disability, microcephaly, and congenital heart defects
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Low nasal bridge, epicanthal folds, protruding tongue, and low-set ears
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Male appearance, infertility, gynecomastia, small testes, sparse body hair, and a high-pitched voice
Question 2
Which of the following cells is the primary phagocyte in the human immune system?
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Goblet cell
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Mast cell
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Neutrophil ✅
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T lymphocyte
Question 3
Deep brain stimulation (DBS) has demonstrated therapeutic benefit in the treatment of which disorder?
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Anxiety disorders
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Manic disorder
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Obsessive-compulsive disorder (OCD) ✅
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Schizophrenia
Question 4
An advanced practice registered nurse (APRN) evaluates a patient with a pulmonary artery occlusion caused by an embolus secondary to venous stasis. Which factor primarily determines the physiological impact of this condition?
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Extent of venous circulation restriction and timing of thrombus formation
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Extent of capillary involvement in returning deoxygenated blood to the heart
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Extent of arterial ability to deliver waste products to tissue cells
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Extent of pulmonary blood flow obstruction and the size of the affected vessels ✅
Question 5
A patient reviews laboratory results with an advanced practice registered nurse (APRN) and asks about the cause of an abnormally low serum albumin level. Which explanation is most appropriate?
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It is caused by the patient’s history of multiple fractures
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It reflects underlying liver damage ✅
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It is related to the patient’s irritable bowel syndrome
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It is caused by the patient’s lymphadenopathy
Question 6
Which normal physiological factor explains why the left ventricle is larger and more muscular than the right ventricle?
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Increased pressure in pulmonary circulation
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Decreased pressure in systemic circulation
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Increased pressure in systemic circulation ✅
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Decreased pressure in pulmonary circulation
Question 7
A patient is suspected of having cholecystitis. What urine color should the nurse anticipate?
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Dark amber ✅
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Red
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Pale yellow
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Greenish brown………………………………………………………$30

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