NR567 Week 8: Final Exam

A patient is being treated with fluoxetine and complains of sexual dysfunction. Which of the following is an appropriate next step?

Answers: A – D

A. Consider switching to another antidepressant with fewer sexual side effects ✅
B. Change dosing instructions to once weekly
C. Add a medication such as sildenafil to improve sexual function
D. Add an additional SSRI to counteract the side effects of the fluoxetine

A patient arrives in the emergency room in status epilepticus. Which medication should be administered first?

Answers: A – D

A. Oxazepam
B. Lorazepam ✅
C. Clonazepam
D. Levetiracetam

A nurse practitioner is counseling a patient who has been prescribed pregabalin for neuropathic pain. What critical information should the nurse include regarding potential adverse effects of this medication?

Answers: A – D

A. Patients may experience significant weight loss
B. Pregabalin is completely free of side effects
C. Pregabalin has a high potential for drug interactions
D. Watch for signs of angioedema, such as swelling of the face and throat ✅

A 65-year-old male diagnosed with early-stage Parkinson’s disease presents with tremors and bradykinesia that interfere with his daily activities. Which medication would be the most appropriate initial pharmacologic treatment to improve his motor function?

Answers: A – D

A. Selegiline
B. Pramipexole ✅
C. Benztropine
D. Entacapone

What is a significant risk associated with the use of allopurinol in patients with renal impairment?

Answers: A – D

A. Acute gout attacks
B. Drug accumulation leading to toxicity ✅
C. Cardiovascular events
D. Severe cutaneous adverse reactions

A patient on cytotoxic chemotherapy develops hyperuricemia. What is the best pharmacologic treatment to prevent complications such as renal failure?

Answers: A – D

A. Allopurinol ✅
B. Methotrexate
C. Furosemide
D. Zoledronic acid

What is a significant contraindication for the use of ergotamine in migraine treatment?

Answers: A – D

A. Smoking history
B. Hypercholesterolemia
C. Peripheral vascular disease ✅
D. Over 40 years old

A 68-year-old patient with moderate Alzheimer’s disease has been prescribed donepezil. Which of the following medications would decrease the therapeutic effect of donepezil?

Answers: A – D

A. First-generation antihistamines ✅
B. Nonsteroidal anti-inflammatory drugs (NSAIDs)
C. Memantine
D. Sodium bicarbonate

A 38-year-old female presents with frequent migraine attacks and has been using ergotamine daily for relief. She now complains of worsening headaches, nausea, vomiting, and restlessness when she skips a dose. What is the most likely cause of her symptoms?

Answers: A – D

A. New onset migraine
B. Allergic reaction to ergotamine
C. Medication overuse headache (MOH) ✅
D. Physical dependence on ergotamine…………………………………………………………$60